No needles, no boosters: extended-release nanovaccines can be delivered by nasal inhaler rather than injection
Nanovaccines don't need refrigeration (polio campaign worker in India carrying styrofoam cooler for vaccine)
Nanotherapeutics use lower dosages than systemic drugs, allowing life-saving drugs to be used for young children
Nanovaccines can prevent respiratory infections such as influenza
Nanoparticles may deliver therapeutic agents across the blood-brain barrier to treat neural disorders such as Alzheimer's, Parkinson's, and stroke
Nanovaccines can prevent tropical diseases such as malaria and filariasis
For cancers, we are researching tumor-specific targets for nanovaccine delivery
Veterinary nanovaccines can prevent viral diseases in farmed shrimp
Nanoparticles average only 300 nanometers in diameter, 1000 times smaller than the period at the end of a sentence.
Our nanovaccine consortium is a diverse, interdisciplinary team (group photo at our August 2014 annual meeting)
Our university research is training the next generation of nanovaccine scientists, including U of Iowa immunology grad student Hailie Fowler (left) and Iowa State veterinary microbiology postdoc Paola Boggiatto
Systems Design of Nanovaccines: Bedside to Bench and Back
We are taking a systems approach to vaccine development that is rooted in science and driven by first principles. This approach, which integrates nanotechnology, materials science, immunology, … Read more
Profiles in Nanomedicine Research: Donald Sakaguchi
"The research in my lab is focused on developing experimental strategies to repair damaged nervous system. We're taking multiple approaches - one of the principal approaches we're taking is called the neuroprotective strategy..." Watch now...
Single Dose Novel Antibody Offers Complete Protection Against Bird Flu
Researchers at St Jude Children's Research Hospital, Stanford University Medical Center, and MacroGenics have developed an antibody which is 100% protective against the deadly bird flu virus in two … Read More
Profiles in Nanomedicine Research: Mike Wannemuehler
"The nanoparticle-specific project is immunologically-focused in my lab, and working with the collaborators down in Chemical and Biological Engineering like Dr. Narasimhan. I’m trying to understand how the nanoparticles interact with antigen-presenting cells..." Watch now...