No needles, no boosters: extended-release nanovaccines can be delivered by nasal inhaler rather than injection
Nanovaccines don't need refrigeration (polio campaign worker in India carrying styrofoam cooler for vaccine)
Nanotherapeutics use lower dosages than systemic drugs, allowing life-saving drugs to be used for young children
Nanovaccines can prevent respiratory infections such as influenza
Nanoparticles may deliver therapeutic agents across the blood-brain barrier to treat neural disorders such as Alzheimer's, Parkinson's, and stroke
Nanovaccines can prevent tropical diseases such as malaria and filariasis
For cancers, we are researching tumor-specific targets for nanovaccine delivery
Veterinary nanovaccines can prevent viral diseases in farmed shrimp
Nanoparticles average only 300 nanometers in diameter, 1000 times smaller than the period at the end of a sentence.
Our nanovaccine consortium is a diverse, interdisciplinary team (group photo at our August 2014 annual meeting)
Our university research is training the next generation of nanovaccine scientists, including U of Iowa immunology grad student Hailie Fowler (left) and Iowa State veterinary microbiology postdoc Paola Boggiatto
Systems Design of Nanovaccines: Bedside to Bench and Back
We are taking a systems approach to vaccine development that is rooted in science and driven by first principles. This approach, which integrates nanotechnology, materials science, immunology, … Read more
Profiles in Nanomedicine Research: Katie Bratlie
"We try to take biomaterials, which are any material that is going to be implanted into a patient, to modify how the body responds. For instance, if we have a cancer drug we’re trying to deliver, we use these materials to deliver the drug but also to interact with the cells..." Watch now...
Aerosol Vaccine Better Protection Against Swine Influenza
Recently published veterinary research at Iowa State University shows that influenza vaccines administered in the upper respiratory system of pigs are more effective in some key respects than standard … Read more
Profiles in Nanomedicine Research: Surya Mallapragada
"Our work mainly deals with coming up with new materials for biomedical applications, so we look at how we can use material-based approaches to help with nerve regeneration, drug and vaccine deliveries and so on..." Watch now...