Inter-organ and inter-organelle communication play an important role in cellular and tissue homeostasis. Dr. Bai will present recent and unpublished work on the novel roles of peroxisome in liver-heart communication and mitochondrial dynamics during animal aging. Peroxisomes are essential and yet the least studied subcellular organelles of all eukaryotic cells. They play a crucial role in the regulation of cellular redox homeostasis, oxidation of very long chain fatty acids (VLCFAs), and biosynthesis of ether phospholipid. Recent studies demonstrated that peroxisomal deficiency is a major cause of aging and that the interplay between peroxisomes and other organelles (e.g., mitochondria) play a crucial role in cellular homeostasis during animal aging.
“Mechanisms of aging: from inter-organ communication to inter-organelle cross-talk”
Hua Bai, PhD
Assistant Professor of Genetics, Development & Cell Biology, Iowa State University
Thursday, September 30, 3:00–4:00 PM CT
If you have any questions about this event, please contact Carly Ross, firstname.lastname@example.org, 515-294-2194